'Genome editing' could correct genetic mutations for future generations
Scientists at Indiana University and colleagues at Stanford and the University of Texas have demonstrated a technique for "editing" the genome in sperm-producing adult stem cells, a result with...
View ArticleFirst real-world trial of impact of patient-controlled access to electronic...
In the first real-world trial of the impact of patient-controlled access to electronic medical records, almost half of the patients who participated withheld clinically sensitive information in their...
View ArticlePatient self-reporting version of 'blood pressure cuff' for dementia is...
The patient self-reporting version of the Healthy Aging Brain Care Monitor—a primary-care tool to measure cognitive, functional and psychological symptoms—is user-friendly, reliable and valid,...
View ArticleOPTIMISTIC: New care model to prevent unnecessary hospitalizations of frail...
A new study from Indiana University and Regenstrief Institute researcher-clinicians reports on the first year of the implementation of OPTIMISTIC, an innovative program they developed and implemented...
View Article100 million Americans live with chronic pain, but treatment research is...
An estimated 100 million Americans live with chronic pain. A new report by an independent panel convened by the National Institutes of Health has found a need for evidence-based, multidisciplinary...
View ArticleAre medications' adverse cognitive effects reversible?
Whether the adverse cognitive effects of medications can be reversed is of significant importance to an aging population, their caregivers and their families, as well as to an overburdened health care...
View ArticleResearcher identifies novel pathway that solid tumor cancer cells activate...
A common, yet previously undistinguished protein, which is elevated in many late-stage cancers, may play a strategic role in tumor growth through a non-conventional pathway, researchers at the Indiana...
View ArticleStudy finds obese black and white women differ in how they view weight
Low-income obese white women uniformly reported that weight negatively affects their lives and causes health problems. But half of their black contemporaries are comfortable with obesity, according to...
View ArticleEditorial issues a call to action for end-of-life care of older adults in...
End-of-life care for nursing home residents has long been associated with poor symptom control and low family satisfaction. With more than one in four older Americans dying in a nursing home—including...
View ArticleMarine oil supplement has positive effects on post-exercise muscle damage
An Indiana University study has revealed that there may be a greater connection between mussels and muscles than previously thought.
View ArticleResearchers identify pancreatic cancer patients who benefit from personalized...
Cancer researchers at Indiana University report that about 15 percent of people with pancreatic cancer may benefit from therapy targeting a newly identified gene signature.
View ArticleNew care model enhances psychological, cognitive and physical recovery of ICU...
The Critical Care Recovery Center care model—the nation's first collaborative care concept focusing on the extensive cognitive, physical and psychological recovery needs of intensive care unit...
View ArticleTwo-step treatment improved function and decreased pain severity in veterans
Although U.S. military veterans who have returned from Iraq or Afghanistan are more likely to suffer chronic pain than veterans of any other conflict in American history, little headway has been made...
View ArticleRegenstrief study finds natural language processing accurately tracks...
An accurate system for tracking the quality of colonoscopies and determining the appropriate intervals between these procedures could contribute to both better health outcomes and lower costs....
View ArticleStudies of health information exchanges yet to show strong evidence of benefits
Health information exchanges are supposed to improve the speed, quality, safety and cost of patient care, but there is little evidence of that in existing health information exchange benefit studies,...
View ArticleBroken cellular communication in brain contributes to Huntington's disease...
Indiana University researchers have found that broken communication in a specific part of the brain plays a role in the involuntary physical movements that affect individuals with Huntington's disease.
View ArticleDiscovering another interoperability challenge in health information exchange
Health information exchange enables clinicians to have secure access to a patient's medical record including details on care received at other locations. But an important piece of information is...
View ArticleImproving the quality of medical care using computer understanding of human...
How can computer-based analysis of free text—the narrative comments found in medical records and expressed in everyday language or technical terminology - help improve the quality of medical care?
View ArticleRegenstrief Institute puts clinicians in charge of computer-based decision...
Electronic medical record systems and computerized physician order entry systems provide clinicians with decision support in the form of warnings or reminders about possible drug interactions,...
View ArticleWorld's largest open source health information technology project tackles Ebola
An accurate, up to the minute, accessible medical record system is fundamental to effective treatment and tracking of the Ebola virus. But how to create this type of system in the rudimentary,...
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